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In the record yearit corresponded to about 5 per cent of the total wind power generated. Dustin to simulate the formation of synapses using computer models. In this way, activation of T-cells may be induced or slowed down, which could be used for improved management of acute or chronic infections, improved results from vaccination or prevention of autoimmune diseases. Both cells form a ring-shaped structure made of different proteins at the point of contact between the cells — termed immunological synapse — over which they can exchange information. Where immunological synapses are correctly formed, the receptor molecules are concentrated around a central point whereas the other surface proteins arrange themselves into two rings around this central area. These are additional expenses which, according to the federal network agency, Bundesnetzagentur, can only be reduced in the long term by expanding the network[1]. Both cells form a characteristic ring-shaped structure at their contact point, the immunological synapse, through which they exchange information. If one of these cells meets a foreign body, it will integrate parts from it — called antigens — onto its own cell surface and present these to other immune cells:

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    Dustin to simulate the formation of synapses using computer models. Where immunological synapses are correctly formed, the receptor molecules are concentrated around a central point whereas the other surface proteins arrange themselves into two rings around this central area.

    At the end of this process the T-cell is either activated or remains inactive. These are additional expenses which, according to the federal network agency, Bundesnetzagentur, can only be reduced in the long term by expanding the network[1].

    With the new system, these flows can be accelerated more than 30 times. They organise themselves in small clusters which are transported by actin in the direction of the centre of the synapse. The loose bond formed between the two cell surfaces allows for the binding of T-cell receptors to the presented antigen.

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    HZI researchers have investigated the formation of immunological synapses over which immune cells exchange information The immune system protects the human body against pathogens thus keeping it healthy.

    This cell type is responsible for classifying the presented parts as dangerous or harmless and, if necessary, initiating a response against them. Researchers of the Helmholtz Centre for Infection Research HZI and the Braunschweig Integrated Centre of Systems Biology BRICSin collaboration with researchers at the University of Oxford UKhave now simulated the dynamic arrangement of these components using computer models and have subsequently been able to make inferences on the mechanisms involved in the formation of synapses.

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    Microscope image shows an immunological synapse. In these models, they simulated different conditions and influencing factors and were able to demonstrate that the different molecules exert an influence on each other in terms of their arrangement although they do not interact directly.

    With the previous technology — the simulation software ran on classic servers — the massive increase in computing power required for this would not have been possible, however, which is also due to the complexity of the German energy system, which has increased enormously in the course of the energy revolution.

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    Both cells form a characteristic ring-shaped structure at their contact point, the immunological synapse, through which they exchange information.

    Navigation and service Go to: At the end of this process the T-cell is either activated or remains inactive. The large adhesion molecules accumulate around them in an outer ring. The grid operator uses computer simulations of the power flows in the grid for the expansion. German transmission grids Copyright:

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    These are additional expenses which, according to the federal network agency, Bundesnetzagentur, can only be reduced in the long term by expanding the network[1].

    For the optimal adaptation and design of new lines, TenneT strives to simulate and optimise the power flows throughout the entire network over a whole year. In this way, activation of T-cells may be induced or slowed down, which could be used for improved management of acute or chronic infections, improved results from vaccination or prevention of autoimmune diseases.

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    Robert, Philippos Demetriou, Michael L. Microscope image shows an immunological synapse.

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    Researchers of the Helmholtz Centre for Infection Research HZI and the Braunschweig Integrated Centre of Systems Biology BRICSin collaboration with researchers at the University of Oxford UKhave now simulated the dynamic arrangement of these components using computer models and have subsequently been able to make inferences on the mechanisms involved in the formation of synapses. Area Menu Media Press releases:

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    The antigen receptors are small and are repelled by the large adhesion molecules.

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    This leaves more time to analyse the calculation results in further dimensions and to obtain new findings. Involved Groups Systems Immunology. Anastasios Siokis, Philippe A.

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    Due to grid bottlenecks, the output power of power plants, wind turbines and photovoltaic systems must on occasion be temporarily limited in order to stabilise grid operation. For the optimal adaptation and design of new lines, TenneT strives to simulate and optimise the power flows throughout the entire network over a whole year.

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    Today, the researchers have published their results in the scientific journal Cell Reports. Cell Reports,DOI: Area Menu Media Press releases: The antigen receptors are small and are repelled by the large adhesion molecules.

    At the end of this process the T-cell is either activated or remains inactive. The grid operator uses computer simulations of the power flows in the grid for the expansion.